Description
CGRP antagonist 1 is a highly potent CGRP receptor antagonist with a Ki and IC50 of 35 and 57 nM, respectively.
Product information
CAS Number: 1123757-49-2
Molecular Weight: 494.54
Formula: C29H26N4O4
Chemical Name: N-[(2S)-2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-6-yl]-2-{2-oxo-1,2-dihydrospiro[indole-3,4'-oxan]-1-yl}acetamide
Smiles: O=C(CN1C2C=CC=CC=2C2(CCOCC2)C1=O)NC1=CC2C[C@@]3(CC=2C=C1)C1=CC=CN=C1NC3=O
InChiKey: HGRHCVKYWPUJJT-LJAQVGFWSA-N
InChi: InChI=1S/C29H26N4O4/c34-24(17-33-23-6-2-1-4-21(23)28(27(33)36)9-12-37-13-10-28)31-20-8-7-18-15-29(16-19(18)14-20)22-5-3-11-30-25(22)32-26(29)35/h1-8,11,14H,9-10,12-13,15-17H2,(H,31,34)(H,30,32,35)/t29-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
CGRP antagonist 1 is compound 20.
Products are for research use only. Not for human use.
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