Description
Alicapistat (ABT-957) is an orally active selective inhibitor of human calpains 1 and 2 for the potential use in the treatment of Alzheimer's disease (AD).
Product information
CAS Number: 1254698-46-8
Molecular Weight: 433.50
Formula: C25H27N3O4
Chemical Name: 3-{[(2R)-1-benzyl-5-oxopyrrolidin-2-yl]formamido}-N-cyclopropyl-2-oxo-4-phenylbutanamide
Smiles: O=C1CC[C@H](C(=O)NC(CC2C=CC=CC=2)C(=O)C(=O)NC2CC2)N1CC1C=CC=CC=1
InChiKey: MMLDHJRGTZHNHV-BPGUCPLFSA-N
InChi: InChI=1S/C25H27N3O4/c29-22-14-13-21(28(22)16-18-9-5-2-6-10-18)24(31)27-20(15-17-7-3-1-4-8-17)23(30)25(32)26-19-11-12-19/h1-10,19-21H,11-16H2,(H,26,32)(H,27,31)/t20?,21-/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (230.68 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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