Description
Entasobulin is a β-tubulin polymerization inhibitor with potential anticancer activity.
Product information
CAS Number: 501921-61-5
Molecular Weight: 439.89
Formula: C26H18ClN3O2
Chemical Name: 2-{1-[(4-chlorophenyl)methyl]-1H-indol-3-yl}-2-oxo-N-(quinolin-6-yl)acetamide
Smiles: O=C(C1=CN(CC2C=CC(Cl)=CC=2)C2=CC=CC=C21)C(=O)NC1=CC2=CC=CN=C2C=C1
InChiKey: LJIUXAHLYIPHOK-UHFFFAOYSA-N
InChi: InChI=1S/C26H18ClN3O2/c27-19-9-7-17(8-10-19)15-30-16-22(21-5-1-2-6-24(21)30)25(31)26(32)29-20-11-12-23-18(14-20)4-3-13-28-23/h1-14,16H,15H2,(H,29,32)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 155 mg/mL (352.36 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Entasobulin is a indolizine-glyoxylamide based small molecule that demonstrate substantial in vitro anti-proliferative activities against cancer cell lines, including multidrug resistance (MDR) phenotypes.
Products are for research use only. Not for human use.
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