Gadolinium chloride


Catalog No. Size PriceQuantity
M19290-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Gadolinium chloride is a specific calcium-sensing receptor (CaSR) agonist. Gadolinium chloride can be used for the research of cardiovascular disease.

Product information

CAS Number: 10138-52-0

Molecular Weight: 263.61

Formula: Cl3Gd

Chemical Name: trichlorogadolinium

Smiles: Cl[Gd](Cl)Cl

InChiKey: MEANOSLIBWSCIT-UHFFFAOYSA-K

InChi: InChI=1S/3ClH.Gd/h3*1H;/q;;;+3/p-3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Gadolinium chloride (30 μM; 15 minutes; H9c2 cells) results in increased Bax expression and caspase-3 activation, and decreased Bcl-2 expression in CsA-induced cells. In vitro, GdCl3, a CaSR agonist, has been shown to promote the apoptosis of myocardial cells, which increases ERK1/2 phosphorylation and activates caspase-3.

Products are for research use only. Not for human use.

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