RI-2


Catalog No. Size PriceQuantity
M19330-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

RI-2 is a reversible RAD51 inhibitor, with an IC50 of 44.17 μM, and specifically inhibits homologous recombination repair in human cells.

Product information

CAS Number: 1417162-36-7

Molecular Weight: 433.28

Formula: C21H18Cl2N2O4

Chemical Name: 1-(3,4-dichlorophenyl)-3-(4-methoxyphenyl)-4-(morpholin-4-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

Smiles: COC1=CC=C(C=C1)C1C(=O)N(C2C=CC(Cl)=C(Cl)C=2)C(=O)C=1N1CCOCC1

InChiKey: JMPJNNOSVCHYOU-UHFFFAOYSA-N

InChi: InChI=1S/C21H18Cl2N2O4/c1-28-15-5-2-13(3-6-15)18-19(24-8-10-29-11-9-24)21(27)25(20(18)26)14-4-7-16(22)17(23)12-14/h2-7,12H,8-11H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 130 mg/mL (300.04 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

RI-2 (7a) is a reversible RAD51 inhibitor, with an IC50 of 44.17 μM. RI-2 specifically inhibits homologous recombination repair in human cells. RI-2 (150 μM) induces a significant sensitization of cells.

Products are for research use only. Not for human use.

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