Description
Carebastine is the active metabolite of Ebastine. Carebastine is a histamine H1 receptor antagonist. Carebastine inhibits VEGF-induced HUVEC and HPAEC proliferation, migration and angiogenesis in a dose-dependent manner. Carebastine suppresses the expression of macrophage migration inhibitory factor.
Product information
CAS Number: 90729-42-3
Molecular Weight: 499.64
Formula: C32H37NO4
Chemical Name: 2-(4-{4-[4-(diphenylmethoxy)piperidin-1-yl]butanoyl}phenyl)-2-methylpropanoic acid
Smiles: CC(C)(C(O)=O)C1=CC=C(C=C1)C(=O)CCCN1CCC(CC1)OC(C1C=CC=CC=1)C1C=CC=CC=1
InChiKey: XGHOVGYJHWQGCC-UHFFFAOYSA-N
InChi: InChI=1S/C32H37NO4/c1-32(2,31(35)36)27-17-15-24(16-18-27)29(34)14-9-21-33-22-19-28(20-23-33)37-30(25-10-5-3-6-11-25)26-12-7-4-8-13-26/h3-8,10-13,15-18,28,30H,9,14,19-23H2,1-2H3,(H,35,36)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 2 mg/mL (4.00 mM; Need ultrasonic and warming).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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