Description
Biphenylindanone A (BINA) is a selective human mGluR2 (hmGluR2) potentiator for the treatment of many neurological disorders.
Product information
CAS Number: 866823-73-6
Molecular Weight: 454.56
Formula: C30H30O4
Chemical Name: 3'-({[(2S)-2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl]oxy}methyl)-[1,1'-biphenyl]-4-carboxylic acid
Smiles: CC1=C(C=C2C[C@@H](C3CCCC3)C(=O)C2=C1C)OCC1C=C(C=CC=1)C1C=CC(=CC=1)C(O)=O
InChiKey: KMKBEESNZAPKMP-SANMLTNESA-N
InChi: InChI=1S/C30H30O4/c1-18-19(2)28-25(15-26(29(28)31)22-7-3-4-8-22)16-27(18)34-17-20-6-5-9-24(14-20)21-10-12-23(13-11-21)30(32)33/h5-6,9-14,16,22,26H,3-4,7-8,15,17H2,1-2H3,(H,32,33)/t26-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Biphenylindanone A (BINA) shows activity on glutamate-induced scintillation proximity assay [3H]IP1 hydrolysis on WT mGluR2 (EC50=1.57 μM) in the absence or presence of 5 μM glutamate.
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.