IDO1-IN-5


Catalog No. Size PriceQuantity
M19566-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

IDO1-IN-5 is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.

Product information

CAS Number: 2166616-75-5

Molecular Weight: 396.45

Formula: C23H25FN2O3

Chemical Name: 4-fluoro-N-[(1R)-1-[1-(oxane-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]ethyl]benzamide

Smiles: C[C@@H](NC(=O)C1C=CC(F)=CC=1)C1C=C2CCN(C(=O)C3CCOCC3)C2=CC=1

InChiKey: NUBWFWVVKLRSHS-OAHLLOKOSA-N

InChi: InChI=1S/C23H25FN2O3/c1-15(25-22(27)16-2-5-20(24)6-3-16)18-4-7-21-19(14-18)8-11-26(21)23(28)17-9-12-29-13-10-17/h2-7,14-15,17H,8-13H2,1H3,(H,25,27)/t15-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 300 mg/mL (756.72 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

IDO1-IN-5 (up to 100 µM) shows no obvious agonism of aryl hydrocarbon receptor (AHR).

Products are for research use only. Not for human use.

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