5, 6-Dihydrouridine


Catalog No. Size PriceQuantity
M19583-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

5,6-Dihydrouridine is a modified base found in conserved positions in the D-loop of tRNA in Bacteria, Eukaryota, and some Archaea.

Product information

CAS Number: 5627-05-4

Molecular Weight: 247.21

Formula: C8H13N3O6

Chemical Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazinane-2,4-dione

Smiles: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1CNC(=O)NC1=O

InChiKey: QNFUDJQAVSWKDP-KVTDHHQDSA-N

InChi: InChI=1S/C8H13N3O6/c12-1-3-4(13)5(14)6(17-3)11-2-9-7(15)10-8(11)16/h3-6,12-14H,1-2H2,(H2,9,10,15,16)/t3-,4-,5-,6-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 125 mg/mL (507.68 mM). H2O : 100 mg/mL (406.14 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

5,6-Dihydrouridine (Dihydrouridine) is one of the posttranscriptionally modified nucleosides. It is a product of the reduction of uridine (U), and can be further modified to 5-methyldihydrouridine (m5D). 5,6-Dihydrouridine is commonly present in the tRNA from Bacteria, Eukaryota, and some Archaea. It is identified in six positions in the “D-loop” of the tRNA (16, 17, 20a, 20b) and in position 47 in the variable loop.

Products are for research use only. Not for human use.

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