Danirixin


Catalog No. Size PriceQuantity
M19594-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Danirixin is a selective, and reversible CXCR2 antagonist, with IC50 of 12.5 nM for CXCL8.

Product information

CAS Number: 954126-98-8

Molecular Weight: 441.90

Formula: C19H21ClFN3O4S

Chemical Name: 1-{4-chloro-2-hydroxy-3-[(3S)-piperidine-3-sulfonyl]phenyl}-3-(3-fluoro-2-methylphenyl)urea

Smiles: CC1C(F)=CC=CC=1NC(=O)NC1=CC=C(Cl)C(=C1O)S(=O)(=O)[C@@H]1CNCCC1

InChiKey: NGYNBSHYFOFVLS-LBPRGKRZSA-N

InChi: InChI=1S/C19H21ClFN3O4S/c1-11-14(21)5-2-6-15(11)23-19(26)24-16-8-7-13(20)18(17(16)25)29(27,28)12-4-3-9-22-10-12/h2,5-8,12,22,25H,3-4,9-10H2,1H3,(H2,23,24,26)/t12-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 8 mg/mL (18.10 mM; Need ultrasonic and warming).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Danirixin is a small molecule, CXCR2 antagonist being evaluated as a potential anti-inflammatory medicine.

Products are for research use only. Not for human use.

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