FR-190809


Catalog No. Size PriceQuantity
M19622-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

FR-190809 is a potent, nonadrenotoxic, orally efficacious acyl-CoA:cholesterol O-acyltransferase (ACAT) inhibitor, with an IC50 of 45 nM.

Product information

CAS Number: 215589-63-2

Molecular Weight: 603.73

Formula: C29H34FN3O6S2

Chemical Name: 1-cycloheptyl-3-(2,4-dimethanesulfonyl-6-methylpyridin-3-yl)-1-{[4-(4-fluorophenoxy)phenyl]methyl}urea

Smiles: CC1=CC(=C(NC(=O)N(CC2C=CC(=CC=2)OC2C=CC(F)=CC=2)C2CCCCCC2)C(=N1)S(C)(=O)=O)S(C)(=O)=O

InChiKey: UFRBZRWETFGORO-UHFFFAOYSA-N

InChi: InChI=1S/C29H34FN3O6S2/c1-20-18-26(40(2,35)36)27(28(31-20)41(3,37)38)32-29(34)33(23-8-6-4-5-7-9-23)19-21-10-14-24(15-11-21)39-25-16-12-22(30)13-17-25/h10-18,23H,4-9,19H2,1-3H3,(H,32,34)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

FR-190809 inhibits foam cell formation with an IC50 of 215 nM.

Products are for research use only. Not for human use.

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