BMS 753


Catalog No. Size PriceQuantity
M19686-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

BMS 753 is an isotype-selective retinoic acid receptor α (RARα) agonist, with a Ki of 2 nM.

Product information

CAS Number: 215307-86-1

Molecular Weight: 351.40

Formula: C21H21NO4

Chemical Name: 4-(1,1,3,3-tetramethyl-2-oxo-2,3-dihydro-1H-indene-5-amido)benzoic acid

Smiles: CC1(C)C2C=C(C=CC=2C(C)(C)C1=O)C(=O)NC1C=CC(=CC=1)C(O)=O

InChiKey: KFBPBWUZXBYJDG-UHFFFAOYSA-N

InChi: InChI=1S/C21H21NO4/c1-20(2)15-10-7-13(11-16(15)21(3,4)19(20)26)17(23)22-14-8-5-12(6-9-14)18(24)25/h5-11H,1-4H3,(H,22,23)(H,24,25)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 50 mg/mL (142.29 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

BMS 753 results in low levels of RARβ transcripts in WT cells, RARγ-/-, but not activates in RARa-/- cells.

Products are for research use only. Not for human use.

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