Description
Cloprostenol sodium salt (ICI 80996 sodium salt) is a potent synthetic prostaglandin analogue, acts as a luteolytic agent, and is a PGF2α receptor agonist.
Product information
CAS Number: 55028-72-3
Molecular Weight: 446.90
Formula: C22H28ClNaO6
Chemical Name: sodium (5E)-7-[(1R,2R,3S,5R)-2-[(1Z,3R)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl]hept-5-enoate
Smiles: [Na+].[O-]C(=O)CCC/C=C/C[C@@H]1[C@@H](/C=C\[C@@H](O)COC2C=C(Cl)C=CC=2)[C@@H](O)C[C@H]1O
InChiKey: IFEJLMHZNQJGQU-XAZIPHFVSA-M
InChi: InChI=1S/C22H29ClO6.Na/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28;/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28);/q;+1/p-1/b3-1+,11-10-;/t16-,18-,19-,20-,21+;/m1./s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: H2O : ≥ 150 mg/mL (335.65 mM).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Cloprostenol is a PGF2α receptor agonist. Cloprostenol (0.1 μM) counteracts the adipogenic effects of statil, on both intracellular lipid accumulation and expression of transcripts for proadipogenic factors C/EBPα and PPARγ after treatment for 6 days.
In Vivo:
Cloprostenol sodium salt (25 μg) decreases plasma progesterone in pregnant rats.
Products are for research use only. Not for human use.
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