Description
RWJ 63556 is an orally active COX-2 selective/5-lipoxygenase inhibitor, with anti-inflammatory activities.
Product information
CAS Number: 190967-35-2
Molecular Weight: 287.33
Formula: C11H10FNO3S2
Chemical Name: N-[5-(4-fluorophenoxy)thiophen-2-yl]methanesulfonamide
Smiles: CS(=O)(=O)NC1=CC=C(OC2C=CC(F)=CC=2)S1
InChiKey: BEIZIEZPGSIQGR-UHFFFAOYSA-N
InChi: InChI=1S/C11H10FNO3S2/c1-18(14,15)13-10-6-7-11(17-10)16-9-4-2-8(12)3-5-9/h2-7,13H,1H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
RWJ 63556 is a potent inhibitor of leukocyte influx over a period of 24 hr and maintains its in vitro profile on eicosanoids.
In Vivo:
RWJ 63556 (1 mg/kg, i.v.) significantly inhibits the development of SP-induced oedema.
Products are for research use only. Not for human use.
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