Description
SCR-1481B1 (c-Met inhibitor 2) is a potent compound that has activity against cancers dependent upon Met activation and also has activity against cancers as a VEGFR inhibitor.
Product information
CAS Number: 1174161-86-4
Molecular Weight: 699.98
Formula: C28H29ClF2N5O10P
Chemical Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol; {[3-({4-[(2-amino-3-chloropyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridin-1-yl]methoxy}phosphonic acid
Smiles: NC1=NC=CC(OC2=CC=C(C=C2F)NC(=O)C2=CN(COP(O)(O)=O)C=C(C3=CC=C(F)C=C3)C2=O)=C1Cl.NC(CO)(CO)CO
InChiKey: SDCKZXWUASKHNF-UHFFFAOYSA-N
InChi: InChI=1S/C24H18ClF2N4O7P.C4H11NO3/c25-21-20(7-8-29-23(21)28)38-19-6-5-15(9-18(19)27)30-24(33)17-11-31(12-37-39(34,35)36)10-16(22(17)32)13-1-3-14(26)4-2-13;5-4(1-6,2-7)3-8/h1-11H,12H2,(H2,28,29)(H,30,33)(H2,34,35,36);6-8H,1-3,5H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : ≥ 100 mg/mL (142.86 mM).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
More details please refer to Patent WO 2009094417 A1.
Products are for research use only. Not for human use.
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