8-Hydroxy-DPAT hydrobromide


Catalog No. Size PriceQuantity
M20050-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-Hydroxy-DPAT hydrobromide has selectivity of almost 1000 fold for a subtype of the 5-HT1 binding site.

Product information

CAS Number: 76135-31-4

Molecular Weight: 328.29

Formula: C16H26BrNO

Chemical Name: (7S)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide

Smiles: Br.CCCN(CCC)[C@@H]1CC2=C(O)C=CC=C2CC1

InChiKey: BATPBOZTBNNDLN-UQKRIMTDSA-N

InChi: InChI=1S/C16H25NO.BrH/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14;/h5-7,14,18H,3-4,8-12H2,1-2H3;1H/t14-;/m0./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) has no effect on 5-HT1B binding at concentrations lower than 100 nM.

In Vivo:

8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide; 32, 56, 80, 100 mg/kg; intramuscularly; 15 min prior to the testing session) of the highest dose significantly interferes with sustained attention and reinforcer efficacy (progressive ratio; PR) performance in the 3,4-methylenedioxymethamphetamine (MDMA)-exposed but not control animals.

Products are for research use only. Not for human use.

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