Buclizine dihydrochloride


Catalog No. Size PriceQuantity
M20423-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Buclizine dihydrochloride is an orally active antihistamine antiallergic compound. Buclizine dihydrochloride is a potent teratogen in the rat.

Product information

CAS Number: 129-74-8

Molecular Weight: 505.95

Formula: C28H35Cl3N2

Chemical Name: 1-[(4-tert-butylphenyl)methyl]-4-[(4-chlorophenyl)(phenyl)methyl]piperazine dihydrochloride

Smiles: Cl.Cl.CC(C)(C)C1C=CC(CN2CCN(CC2)C(C2C=CC=CC=2)C2C=CC(Cl)=CC=2)=CC=1

InChiKey: SDBHDSZKNVDKNU-UHFFFAOYSA-N

InChi: InChI=1S/C28H33ClN2.2ClH/c1-28(2,3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-15-26(29)16-12-24;;/h4-16,27H,17-21H2,1-3H3;2*1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 2.5 mg/mL (4.94 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Buclizine (0-100 μM, 72 h) inhibits cancer cell growth by binding to TCTP and induction of cell differentiation.

In Vivo:

Buclizine dihydrochloride (≥40 mg/kg) exhibits teratogenic effect. Buclizine dihydrochloride exhibits the t1/2 of ~10 h via oral administration.

Products are for research use only. Not for human use.

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