Description
Dynamin inhibitory peptide competitively blocks binding of dynamin to amphiphysin, thus preventing endocytosis. Dynamin inhibitory peptide blocks the dopamine D3 effect on GABAA receptors.
Product information
CAS Number: 251634-21-6
Molecular Weight: 1121.25
Formula: C47H80N18O14
Chemical Name: 1-[2-(2-{2-[(1-{2-[2-({1-[2-(2-amino-4-carbamoylbutanamido)-3-methylbutanoyl]pyrrolidin-2-yl}formamido)-3-hydroxypropanamido]-5-[(diaminomethylidene)amino]pentanoyl}pyrrolidin-2-yl)formamido]-3-carbamoylpropanamido}-5-[(diaminomethylidene)amino]pentanamido)propanoyl]pyrrolidine-2-carboxylic acid
Smiles: CC(C)C(NC(=O)C(N)CCC(N)=O)C(=O)N1CCCC1C(=O)NC(CO)C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NC(CC(N)=O)C(=O)NC(CCCN=C(N)N)C(=O)NC(C)C(=O)N1CCCC1C(O)=O
InChiKey: LHQOQXYEPUSHJL-UHFFFAOYSA-N
InChi: InChI=1S/C47H80N18O14/c1-23(2)35(62-36(69)25(48)14-15-33(49)67)44(77)64-19-7-12-31(64)41(74)61-29(22-66)39(72)59-27(10-5-17-56-47(53)54)43(76)63-18-6-11-30(63)40(73)60-28(21-34(50)68)38(71)58-26(9-4-16-55-46(51)52)37(70)57-24(3)42(75)65-20-8-13-32(65)45(78)79/h23-32,35,66H,4-22,48H2,1-3H3,(H2,49,67)(H2,50,68)(H,57,70)(H,58,71)(H,59,72)(H,60,73)(H,61,74)(H,62,69)(H,78,79)(H4,51,52,55)(H4,53,54,56)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Dynamin inhibitory peptide (50 μM) inhibits GABAAR endocytosis.
Products are for research use only. Not for human use.
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