4-Butylresorcinol


Catalog No. Size PriceQuantity
M20516-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

4-Butylresorcinol is a phenol derivative which can inhibit tyrosinase with IC50 of 11.27 μM.

Product information

CAS Number: 18979-61-8

Molecular Weight: 166.22

Formula: C10H14O2

Chemical Name: 4-butylbenzene-1,3-diol

Smiles: CCCCC1C=CC(O)=CC=1O

InChiKey: CSHZYWUPJWVTMQ-UHFFFAOYSA-N

InChi: InChI=1S/C10H14O2/c1-2-3-4-8-5-6-9(11)7-10(8)12/h5-7,11-12H,2-4H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 150 mg/mL (902.42 mM; Need ultrasonic and warming).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

It shows that 4-Butylresorcinol (4-n-butylresorcinol) significantly inhibits melanin synthesis in a concentration-dependent manner. In addition, it is also found to inhibit the activity of tyrosinase, the rate-limiting melanogenic enzyme. 4-Butylresorcinol does not induce ERK, Akt activation, or MITF degradation, and has no effect on cAMP response element binding protein (CREB) phosphorylation, which stimulates MITF expression. 4-Butylresorcinol strongly reduces tyrosinase activity in a cell-free system. Moreover, 4-Butylresorcinol shows an additive effect in combination with hinokitiol, which reduces MITF expression.

Products are for research use only. Not for human use.

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