1-Ethynylnaphthalene


Catalog No. Size PriceQuantity
M20537-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

1-Ethynylnaphthalene is a selective inhibitor of cytochrome P450 1B1.

Product information

CAS Number: 15727-65-8

Molecular Weight: 152.19

Formula: C12H8

Chemical Name: 1-ethynylnaphthalene

Smiles: C#CC1C=CC=C2C=CC=CC2=1

InChiKey: MCZUXEWWARACSP-UHFFFAOYSA-N

InChi: InChI=1S/C12H8/c1-2-10-7-5-8-11-6-3-4-9-12(10)11/h1,3-9H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 125 mg/mL (821.34 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

1-Ethynylnaphthalene, selective inhibitor of cytochrome P450 IB1, does not affect 2-hydroxylation but inhibits 4-hydroxylation by 38%. At higher concentrations, 1-Ethynylnaphthalene inhibits 2-hydroxylation of 2-Hydroxylation of estradiol (E2) by ~30% and 4-hydroxylation of E2 by up to 80%.

Products are for research use only. Not for human use.

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