PF-06263276


Catalog No. Size PriceQuantity
M20559-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

PF-06263276 (PF 6263276) is a potent and selective pan-JAK inhibitor, with IC50s of 2.2 nM, 23.1 nM, 59.9 nM and 29.7 nM for JAK1, JAK2, JAK3 and TYK2, respectively.

Product information

CAS Number: 1421502-62-6

Molecular Weight: 566.63

Formula: C31H31FN8O2

Chemical Name: 5-ethyl-2-fluoro-4-(3-{5-[5-(piperidin-1-yl)pyrazine-2-carbonyl]-3H,4H,5H,6H,7H-imidazo[4,5-c]pyridin-2-yl}-1H-indazol-6-yl)phenol

Smiles: CCC1=CC(O)=C(F)C=C1C1=CC2NN=C(C3NC4CN(CCC=4N=3)C(=O)C3C=NC(=CN=3)N3CCCCC3)C=2C=C1

InChiKey: XDJGNPSZQSWJCV-UHFFFAOYSA-N

InChi: InChI=1S/C31H31FN8O2/c1-2-18-13-27(41)22(32)14-21(18)19-6-7-20-24(12-19)37-38-29(20)30-35-23-8-11-40(17-26(23)36-30)31(42)25-15-34-28(16-33-25)39-9-4-3-5-10-39/h6-7,12-16,41H,2-5,8-11,17H2,1H3,(H,35,36)(H,37,38)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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