L162389


Catalog No. Size PriceQuantity
M20560-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

L162389 is a potent antagonist of angiotensin AT1 receptor with Ki of 28 nM.

Product information

CAS Number: 169281-53-2

Molecular Weight: 562.72

Formula: C31H38N4O4S

Chemical Name: butyl N-{[4'-({2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl}methyl)-5-propyl-[1,1'-biphenyl]-2-yl]sulfonyl}carbamate

Smiles: CCCCOC(=O)NS(=O)(=O)C1=CC=C(CCC)C=C1C1C=CC(CN2C(CC)=NC3C2=NC(C)=CC=3C)=CC=1

InChiKey: MLGCITBDCGSKQS-UHFFFAOYSA-N

InChi: InChI=1S/C31H38N4O4S/c1-6-9-17-39-31(36)34-40(37,38)27-16-13-23(10-7-2)19-26(27)25-14-11-24(12-15-25)20-35-28(8-3)33-29-21(4)18-22(5)32-30(29)35/h11-16,18-19H,6-10,17,20H2,1-5H3,(H,34,36)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

L-162,389 stimulates phosphatidylinositol turnover, albeit only to a small percentage of the angiotensin response. L-162,389 acts as angiotensin antagonist with IC50 value of 105 nM.

Products are for research use only. Not for human use.

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