Fenobam


Catalog No. Size PriceQuantity
M20651-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Fenobam is a selective, orally active, and brain-penetrant mGluR5 antagonist acting at an allosteric modulatory site (Kds of 54 and 31 nM for rat and human recombinant mGlu5 receptors, respectively). Fenobam displays inverse agonist activity which blocks the mGlu5 receptor basal activity with an IC50 of 84 nM. Fenobam exerts anxiolytic activity.

Product information

CAS Number: 57653-26-6

Molecular Weight: 266.68

Formula: C11H11ClN4O2

Chemical Name: 1-(3-chlorophenyl)-3-(1-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)urea

Smiles: CN1CC(=O)N=C1NC(=O)NC1C=C(Cl)C=CC=1

InChiKey: DWPQODZAOSWNHB-UHFFFAOYSA-N

InChi: InChI=1S/C11H11ClN4O2/c1-16-6-9(17)14-10(16)15-11(18)13-8-4-2-3-7(12)5-8/h2-5H,6H2,1H3,(H2,13,14,15,17,18)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

Fenobam sulfate (30-60 mg/kg; p.o.) significantly inhibited cocaine self-administration .

Products are for research use only. Not for human use.

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