INO-1001


Catalog No. Size PriceQuantity
M20801-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

INO-1001 is a potent and selective poly (ADP-ribose) polymerase (PARP) inhibitor. INO-1001 is a potent enhancer of radiation sensitivity and enhances radiation-induced cell killing by interfering with DNA repair mechanisms, resulting in necrotic cell death. INO-1001 has anti-tumor effects.

Product information

CAS Number: 501364-82-5

Molecular Weight: 439.53

Formula: C23H25N3O4S

Chemical Name: N-[3-(morpholin-4-yl)propyl]-5-oxo-5H,6H,11H-indeno[1,2-c]isoquinoline-9-sulfonamide

Smiles: O=C1NC2=C(CC3C=C(C=CC=32)S(=O)(=O)NCCCN2CCOCC2)C2=CC=CC=C12

InChiKey: LTZVLHHIAUKGBP-UHFFFAOYSA-N

InChi: InChI=1S/C23H25N3O4S/c27-23-20-5-2-1-4-19(20)21-15-16-14-17(6-7-18(16)22(21)25-23)31(28,29)24-8-3-9-26-10-12-30-13-11-26/h1-2,4-7,14,24H,3,8-13,15H2,(H,25,27)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 31.25 mg/mL (71.10 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

INO-1001 has an IC50 of 0.05 μM in Chinese hamster ovary AA8 (CHO) cells.

Products are for research use only. Not for human use.

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