Olafertinib


Catalog No. Size PriceQuantity
M20874-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Olafertinib is a third-generation EGFR TKI, with GI50 values of 5 nM (EGFR L858R/T790M), 10 nM (EGFR del19) and 689 nM (EGFR WT), respectively. Olafertinib has the potential for NSCLC research.

Product information

CAS Number: 1660963-42-7

Molecular Weight: 530.57

Formula: C29H28F2N6O2

Chemical Name: N-{3-[2-({2,3-difluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl}amino)quinazolin-8-yl]phenyl}prop-2-enamide

Smiles: C=CC(=O)NC1C=C(C=CC=1)C1=CC=CC2C=NC(NC3C=CC(=C(F)C=3F)N3CCN(CCO)CC3)=NC=21

InChiKey: IDRGFNPZDVBSSE-UHFFFAOYSA-N

InChi: InChI=1S/C29H28F2N6O2/c1-2-25(39)33-21-7-3-5-19(17-21)22-8-4-6-20-18-32-29(35-28(20)22)34-23-9-10-24(27(31)26(23)30)37-13-11-36(12-14-37)15-16-38/h2-10,17-18,38H,1,11-16H2,(H,33,39)(H,32,34,35)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 125 mg/mL (235.60 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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