PSN 375963 hydrochloride


Catalog No. Size PriceQuantity
M20885-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

PSN 375963 hydrochloride is a potent GPR119 agonist, with EC50s of 8.4 and 7.9 μM for human and mouse GPR119, respectively. PSN 375963 hydrochloride shows similar potency to the endogenous agonist oleoylethanolamide (OEA).

Product information

CAS Number: 1781834-82-9

Molecular Weight: 321.84

Formula: C17H24ClN3O

Chemical Name: 4-{5-[(1s,4r)-4-butylcyclohexyl]-1,2,4-oxadiazol-3-yl}pyridine hydrochloride

Smiles: Cl.CCCC[C@@H]1CC[C@H](CC1)C1=NC(=NO1)C1=CC=NC=C1

InChiKey: ONDLSENXTCSHGC-IOJSEOPQSA-N

InChi: InChI=1S/C17H23N3O.ClH/c1-2-3-4-13-5-7-15(8-6-13)17-19-16(20-21-17)14-9-11-18-12-10-14;/h9-13,15H,2-8H2,1H3;1H/t13-,15-;

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

The endogenous ligand OEA signals through GPR119 in a manner similar to glucagon-like peptide-1 (GLP-1) and its receptor with respect to insulin secretion, intracellular calcium and cAMP.

Products are for research use only. Not for human use.

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