Abemaciclib metabolite M20


Catalog No. Size PriceQuantity
M20949-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Abemaciclib metabolite M20 (LSN3106726), the active metabolite of Abemaciclib, is a selective CDK4/6 inhibitor for the treatment of cancer.

Product information

CAS Number: 2138499-06-4

Molecular Weight: 522.59

Formula: C27H32F2N8O

Chemical Name: {6-[2-({5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}amino)-5-fluoropyrimidin-4-yl]-4-fluoro-1-(propan-2-yl)-1H-1,3-benzodiazol-2-yl}methanol

Smiles: CCN1CCN(CC2=CN=C(C=C2)NC2N=C(C3=CC(F)=C4N=C(CO)N(C(C)C)C4=C3)C(F)=CN=2)CC1

InChiKey: KUJBDJBMXOTNIT-UHFFFAOYSA-N

InChi: InChI=1S/C27H32F2N8O/c1-4-35-7-9-36(10-8-35)15-18-5-6-23(30-13-18)32-27-31-14-21(29)25(34-27)19-11-20(28)26-22(12-19)37(17(2)3)24(16-38)33-26/h5-6,11-14,17,38H,4,7-10,15-16H2,1-3H3,(H,30,31,32,34)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 5 mg/mL (9.57 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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