Description
CHK-IN-1 is an inhibitor of CHK1 and CHK2, with anti-proliferative activities.
Product information
CAS Number: 1278405-51-8
Molecular Weight: 407.89
Formula: C18H19ClFN5OS
Chemical Name: 2-(3-fluorophenyl)-4-{[(3S)-piperidin-3-yl]amino}thieno[2,3-d]pyridazine-7-carboxamide hydrochloride
Smiles: Cl.NC(=O)C1=NN=C(N[C@@H]2CNCCC2)C2C=C(SC=21)C1C=C(F)C=CC=1
InChiKey: UQMQCIABCNUZPU-YDALLXLXSA-N
InChi: InChI=1S/C18H18FN5OS.ClH/c19-11-4-1-3-10(7-11)14-8-13-16(26-14)15(17(20)25)23-24-18(13)22-12-5-2-6-21-9-12;/h1,3-4,7-8,12,21H,2,5-6,9H2,(H2,20,25)(H,22,24);1H/t12-;/m0./s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
CHK-IN-1 can prevent DNA damage repair mechanism from arresting the cell cycle at the G2/M checkpoint.
Products are for research use only. Not for human use.
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