Description
AST2818 mesylate is an EGFR inhibitor.
Product information
CAS Number: 2130958-55-1
Molecular Weight: 664.70
Formula: C29H35F3N8O5S
Chemical Name: N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)prop-2-enamide; methanesulfonic acid
Smiles: CN(C)CCN(C)C1=NC(OCC(F)(F)F)=C(C=C1NC(=O)C=C)NC1N=C(C=CN=1)C1=CN(C)C2C=CC=CC1=2.CS(O)(=O)=O
InChiKey: WDPGHXINXNBHAS-UHFFFAOYSA-N
InChi: InChI=1S/C28H31F3N8O2.CH4O3S/c1-6-24(40)33-21-15-22(26(41-17-28(29,30)31)36-25(21)38(4)14-13-37(2)3)35-27-32-12-11-20(34-27)19-16-39(5)23-10-8-7-9-18(19)23;1-5(2,3)4/h6-12,15-16H,1,13-14,17H2,2-5H3,(H,33,40)(H,32,34,35);1H3,(H,2,3,4)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 5 mg/mL (7.52 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
AST2818 mesylate is designed to inhibit EGFR active mutations as well as the T790M acquired resistant mutation.
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
