Iganidipine


Catalog No. Size PriceQuantity
M21104-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Iganidipine is a Ca2+ antagonist.

Product information

CAS Number: 119687-33-1

Molecular Weight: 526.62

Formula: C28H38N4O6

Chemical Name: 3-{2,2-dimethyl-3-[4-(prop-2-en-1-yl)piperazin-1-yl]propyl} 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Smiles: COC(=O)C1C(C(C(=O)OCC(C)(C)CN2CCN(CC=C)CC2)=C(C)NC=1C)C1C=C(C=CC=1)[N+]([O-])=O

InChiKey: QBTSPDQKRVMTRU-UHFFFAOYSA-N

InChi: InChI=1S/C28H38N4O6/c1-7-11-30-12-14-31(15-13-30)17-28(4,5)18-38-27(34)24-20(3)29-19(2)23(26(33)37-6)25(24)21-9-8-10-22(16-21)32(35)36/h7-10,16,25,29H,1,11-15,17-18H2,2-6H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

Iganidipine (0.03% solution) significantly increases optic nerve head (ONH) tissue blood velocity (NBONH) by 8 to 10% in treated eyes after a single administration (p<0.05) or by 18 to 35% after 7-, 14-, or 21-day twicedaily administration in rabbits (p<0.05). In monkeys, 0.03% and 0.1% Iganidipine significantly increases NBONH in treated eyes by 20 and 41% after 7-day (p<0.05) twice-daily administration, respectively.

Products are for research use only. Not for human use.

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