Desaminotyrosine


Catalog No. Size PriceQuantity
M21151-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.

Product information

CAS Number: 501-97-3

Molecular Weight: 166.17

Formula: C9H10O3

Chemical Name: 3-(4-hydroxyphenyl)propanoic acid

Smiles: OC1C=CC(CCC(O)=O)=CC=1

InChiKey: NMHMNPHRMNGLLB-UHFFFAOYSA-N

InChi: InChI=1S/C9H10O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-2,4-5,10H,3,6H2,(H,11,12)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (601.76 mM; Need ultrasonic). H2O : 33.33 mg/mL (200.57 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

Wild-type mice produce nanomoles of Desaminotyrosine per gram of feces and have picomolar quantities of Desaminotyrosine in the serum. Desaminotyrosine (200 mM) treatment before influenza infection, protects from influenza by type I interferon (IFN) signaling, with no effect on weight loss or survival in mice with or without vancomycin, neomycin, ampicillin, and metronidazole (VNAM). Desaminotyrosine enhances type I IFN in macrophages via type I IFN amplification in mice.

Products are for research use only. Not for human use.

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