3', 4'-Dihydroxyflavonol


Catalog No. Size PriceQuantity
M21470-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

3',4'-Dihydroxyflavonol (DiOHF) is an effective antioxidant, which reduces superoxide and improves nitric oxide (NO) function in diabetic rat mesenteric arteries.

Product information

CAS Number: 6068-78-6

Molecular Weight: 270.24

Formula: C15H10O5

Chemical Name: 2-(3,4-dihydroxyphenyl)-3-hydroxy-4H-chromen-4-one

Smiles: OC1=CC(=CC=C1O)C1OC2C=CC=CC=2C(=O)C=1O

InChiKey: KPGMHZQXQVDYNT-UHFFFAOYSA-N

InChi: InChI=1S/C15H10O5/c16-10-6-5-8(7-11(10)17)15-14(19)13(18)9-3-1-2-4-12(9)20-15/h1-7,16-17,19H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

3',4'-Dihydroxyflavonol (DiOHF) acutely preserves nitric oxide (NO) activity in the presence of elevated reactive oxygen species (ROS). DiOHF improves NO activity in diabetes by reducing Nox2-dependent superoxide production and preventing eNOS uncoupling to improve endothelial function. 3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²⁺ desensitization in permeabilized third-order branches of rat mesenteric arteries.

Products are for research use only. Not for human use.

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