PROTAC BRD4 ligand-1


Catalog No. Size PriceQuantity
M21497-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

PROTAC BRD4 ligand-1 is a potent BET inhibitor and a ligand for target BRD4 protein for PROTACT GNE-987 (HY-129937A).

Product information

CAS Number: 2313230-51-0

Molecular Weight: 500.47

Formula: C23H18F2N4O5S

Chemical Name: 8-(3,5-difluoropyridin-2-yl)-4-(methanesulfonylmethyl)-15-methyl-14-oxo-8,12,15-triazatetracyclo[8.6.1.0²,⁷.0¹³,¹⁷]heptadeca-1(16),2,4,6,10,13(17)-hexaene-5-carboxylic acid

Smiles: CN1C=C2C3=C(NC=C3CN(C3=NC=C(F)C=C3F)C3=CC(C(O)=O)=C(CS(C)(=O)=O)C=C32)C1=O

InChiKey: BSYGSSMAXOMCQE-UHFFFAOYSA-N

InChi: InChI=1S/C23H18F2N4O5S/c1-28-9-16-15-3-11(10-35(2,33)34)14(23(31)32)5-18(15)29(21-17(25)4-13(24)7-27-21)8-12-6-26-20(19(12)16)22(28)30/h3-7,9,26H,8,10H2,1-2H3,(H,31,32)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 5 mg/mL (9.99 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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