Indolmycin


Catalog No. Size PriceQuantity
M21524-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Indolmycin (TAK-083), an antibiotic, is a competitive inhibitor of prokaryotic tryptophanyl-tRNA ligase (TrpS). Indolmycin (TAK-083) possesses both anti-viral and anti-bacterial activity.

Product information

CAS Number: 21200-24-8

Molecular Weight: 257.29

Formula: C14H15N3O2

Chemical Name: (5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-4,5-dihydro-1,3-oxazol-4-one

Smiles: C[C@@H]([C@@H]1OC(NC)=NC1=O)C1=CNC2=CC=CC=C21

InChiKey: GNTVWGDQPXCYBV-PELKAZGASA-N

InChi: InChI=1S/C14H15N3O2/c1-8(12-13(18)17-14(15-2)19-12)10-7-16-11-6-4-3-5-9(10)11/h3-8,12,16H,1-2H3,(H,15,17,18)/t8-,12+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Indolmycin was bacteriostatic and demonstrated good activity against MSSA (methicillinsusceptible Staphylococcus aureus), MRSA (methicillin-resistant S. aureus) and VISA (vancomycinintermediate S. aureus), including strains resistant to mupirocin or fusidic acid. Indolmycin MICs for 20 strains ranged from 8 to 32 mg/L, whereas asingle strain exhibited high-level resistance (MIC 128 mg/L).

Products are for research use only. Not for human use.

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