CP-471474


Catalog No. Size PriceQuantity
M21867-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

CP-471474 is an orally active and pan MMP inhibitor, with IC50 values of 1170 nM (MMP-1), 0.7 nM (MMP-2), 16 nM (MMP-3), 13 nM (MMP-9) and 0.9 nM (MMP-13), respectively.

Product information

CAS Number: 210755-45-6

Molecular Weight: 368.38

Formula: C16H17FN2O5S

Chemical Name: 2-[4-(4-fluorophenoxy)benzenesulfonamido]-N-hydroxy-2-methylpropanamide

Smiles: CC(C)(NS(=O)(=O)C1=CC=C(C=C1)OC1=CC=C(F)C=C1)C(=O)NO

InChiKey: QCOQJYRPDUMCNP-UHFFFAOYSA-N

InChi: InChI=1S/C16H17FN2O5S/c1-16(2,15(20)18-21)19-25(22,23)14-9-7-13(8-10-14)24-12-5-3-11(17)4-6-12/h3-10,19,21H,1-2H3,(H,18,20)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

CP-471474 plasma levels following subcutaneous injection are 2,020 ng/mL (1 h postdose) to 160 ng/mL (6 h postdose). CP-471,474 significantly reduces both the extent and severity of inflammation at 2 months. At 4 months, a spontaneous reduction of the inflammatory response is observed in both treated and untreated animals, and consequently no difference is observed between both. CP-471474 significantly decreases the destructive lesions mainly at 2 months and also at 4 months.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

You may also like

Recently viewed