Description
PPA-904 is a specific phenothiazine photosensitizer in photodynamic therapy (PDT) research, especially topical application for cutaneous leishmaniasis in vivo.
Product information
CAS Number: 30189-85-6
Molecular Weight: 532.62
Formula: C28H42BrN3S
Chemical Name: 3,7-bis(dibutylamino)-5λ⁴-phenothiazin-5-ylium bromide
Smiles: [Br-].CCCCN(CCCC)C1=CC2[S+]=C3C=C(C=CC3=NC=2C=C1)N(CCCC)CCCC
InChiKey: LLMPBOPIZQTTLB-UHFFFAOYSA-M
InChi: InChI=1S/C28H42N3S.BrH/c1-5-9-17-30(18-10-6-2)23-13-15-25-27(21-23)32-28-22-24(14-16-26(28)29-25)31(19-11-7-3)20-12-8-4;/h13-16,21-22H,5-12,17-20H2,1-4H3;1H/q+1;/p-1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
PPA904-PDT can provide an immunomodulating, dose-dependent efflux on IL-12p70 production. This mechanism could be responsible for promoting a more rapid healing in PPA904-PDT treated mice.
Products are for research use only. Not for human use.
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