Description
Chymostatin is a bioactive peptide of microbial origin that acts as a protease inhibitor with selectivity for chymotryptase-like serine proteases. It potently inhibits chymotrypsin and chymase (Ki = 9.36 and 13.1 nM, respectively) while less effectively blocking the activity of cathepsins, papain, and leukocyte elastase.,,,, It is without effect on trypsin, thrombin, plasmin, pepsin, and kallikrein.
Product information
CAS Number: 9076-44-2
Molecular Weight: 607.70
Formula: C31H41N7O6
Chemical Name: (2R)-2-({[(R)-[(4R)-2-amino-3,4,5,6-tetrahydropyrimidin-4-yl]({[(1R)-3-methyl-1-{[(2R)-1-oxo-3-phenylpropan-2-yl]carbamoyl}butyl]carbamoyl})methyl]carbamoyl}amino)-3-phenylpropanoic acid
Smiles: CC(C)C[C@@H](NC(=O)[C@H](NC(=O)N[C@H](CC1=CC=CC=C1)C(O)=O)[C@H]1CCN=C(N)N1)C(=O)N[C@H](CC1=CC=CC=C1)C=O
InChiKey: MRXDGVXSWIXTQL-ZFXZZAOISA-N
InChi: InChI=1S/C31H41N7O6/c1-19(2)15-24(27(40)34-22(18-39)16-20-9-5-3-6-10-20)35-28(41)26(23-13-14-33-30(32)36-23)38-31(44)37-25(29(42)43)17-21-11-7-4-8-12-21/h3-12,18-19,22-26H,13-17H2,1-2H3,(H,34,40)(H,35,41)(H,42,43)(H3,32,33,36)(H2,37,38,44)/t22-,23-,24-,25-,26-/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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