HIF-1 inhibitor-1


Catalog No. Size PriceQuantity
M22589-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

HIF-1 inhibitor-1 is an aryl carboxamide compound and a potent hypoxia-inducible factor 1 (HIF-1) inhibitor with an IC50 of 0.32 μM for the cancer metastasi. . Liu M, et al. Discovery of Novel Aryl Carboxamide Derivatives as Hypoxia-Inducible Factor 1α Signaling Inhibitors with Potent Activities of Anticancer Metastasis. J Med Chem. 2019 Oct 24;62(20):9299-9314.

Product information

CAS Number: 2380261-53-8

Molecular Weight: 350.39

Formula: C21H19FN2O2

Chemical Name: N-[2-(2-fluorophenyl)ethyl]-5-(2-methoxyphenyl)pyridine-2-carboxamide

Smiles: COC1=CC=CC=C1C1=CN=C(C=C1)C(=O)NCCC1=CC=CC=C1F

InChiKey: JZEJSNMITKBPGZ-UHFFFAOYSA-N

InChi: InChI=1S/C21H19FN2O2/c1-26-20-9-5-3-7-17(20)16-10-11-19(24-14-16)21(25)23-13-12-15-6-2-4-8-18(15)22/h2-11,14H,12-13H2,1H3,(H,23,25)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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