SANT-2


Catalog No. Size PriceQuantity
M22784-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

SANT-2 is a Smoothened (Smo) receptor antagonist., It binds to the Smo receptor (Kd = 12 nM) and inhibits binding of the Smo receptor agonist SAG-1.3 and antagonist cyclopamine(Kis = 7.8 and 8.4 nM, respectively). SANT-2 inhibits hedgehog signaling induced by an N-terminal fragment of sonic hedgehog (Shh) in an Shh-LIGHT2 cellular assay (IC50 = 30 nM).

Product information

CAS Number: 329196-48-7

Molecular Weight: 479.96

Formula: C26H26ClN3O4

Chemical Name: N-[3-(1H-1,3-benzodiazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide

Smiles: CCOC1C=C(C=C(OCC)C=1OCC)C(=O)NC1=CC(=C(Cl)C=C1)C1NC2=CC=CC=C2N=1

InChiKey: VQOJFGFKIVFMDH-UHFFFAOYSA-N

InChi: InChI=1S/C26H26ClN3O4/c1-4-32-22-13-16(14-23(33-5-2)24(22)34-6-3)26(31)28-17-11-12-19(27)18(15-17)25-29-20-9-7-8-10-21(20)30-25/h7-15H,4-6H2,1-3H3,(H,28,31)(H,29,30)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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