Interleukin II (60-70)

Interleukin II (60-70), (C68H104N14O14S), is a peptide with the sequence NH2- LEU-THR-PHE-LYS-PHE-TYR-MET-PRO-LYS-LYS-ALA-COOH, MW= 1373.7. Interleukin 2 (IL-2) is a type of cytokine signaling molecule in the immune system, and it regulates the activities of the white blood cells (leukocytes, often lymphocytes) responsible for immunity. IL-2, a soluble hormone-like mediator of the immune system, was the first interleukin molecule to be identified and characterized. IL-2 is necessary for the growth, proliferation, and differentiation of T cells to become 'effector' T cells. IL-2 is normally produced by T cells during an immune response. It is necessary for the development of T cell immunologic memory, which depends upon the expansion of the number and function of antigen-selected T cell clones.IL-2 is also necessary for the maturation of a subset of T cells, termed regulatory T cells, during T cell development in the thymus.

Product information

Molecular Weight: 1373.70

Formula: C68H104N14O14S

Chemical Name: (2S)-2-[(2S)-6-amino-2-[(2S)-6-amino-2-{[(2R)-1-[(2R)-2-[(2R)-2-[(2R)-2-[(2R)-6-amino-2-[(2R)-2-[(2R,3R)-2-[(2S)-2-amino-4-methylpentanamido]-3-hydroxybutanamido]-3-phenylpropanamido]hexanamido]-3-phenylpropanamido]-3-(4-hydroxyphenyl)propanamido]-4-(methylsulfanyl)butanoyl]pyrrolidin-2-yl]formamido}hexanamido]hexanamido]propanoic acid

Smiles: CC(C)C[C@H](N)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@H](CC1=CC=CC=C1)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CC1=CC=CC=C1)C(=O)N[C@H](CC1=CC=C(O)C=C1)C(=O)N[C@H](CCSC)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(O)=O

InChiKey: BSLCXMMYEBIFKY-QPVVYSBHSA-N

InChi: InChI=1S/C68H104N14O14S/c1-41(2)37-48(72)58(85)81-57(43(4)83)66(93)80-55(39-45-21-10-7-11-22-45)62(89)75-50(24-13-16-33-70)61(88)78-53(38-44-19-8-6-9-20-44)64(91)79-54(40-46-27-29-47(84)30-28-46)63(90)77-52(31-36-97-5)67(94)82-35-18-26-56(82)65(92)76-51(25-14-17-34-71)60(87)74-49(23-12-15-32-69)59(86)73-42(3)68(95)96/h6-11,19-22,27-30,41-43,48-57,83-84H,12-18,23-26,31-40,69-72H2,1-5H3,(H,73,86)(H,74,87)(H,75,89)(H,76,92)(H,77,90)(H,78,88)(H,79,91)(H,80,93)(H,81,85)(H,95,96)/t42-,43+,48-,49-,50+,51-,52+,53+,54+,55+,56+,57+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.