Description
Desmethyl ferroquine (SSR97213) is the active and major metabolite of Ferroquine. Ferroquine is an antimalarial. Desmethyl ferroquine shows significant activity against Chloroquine-susceptible and resistant P. falciparum strains.
Product information
CAS Number: 903546-18-9
Molecular Weight: 419.73
Formula: C22H22ClFeN3
Chemical Name: λ²-iron(2+) 1-{[(7-chloroquinolin-4-yl)amino]methyl}-2-[(methylamino)methyl]cyclopenta-2,4-dien-1-ide cyclopenta-2,4-dien-1-ide
Smiles: [Fe+2].CNCC1=CC=C[C-]1CNC1=CC=NC2=CC(Cl)=CC=C21.[CH-]1C=CC=C1
InChiKey: AKDMMOAFGKYNKP-UHFFFAOYSA-N
InChi: InChI=1S/C17H17ClN3.C5H5.Fe/c1-19-10-12-3-2-4-13(12)11-21-16-7-8-20-17-9-14(18)5-6-15(16)17;1-2-4-5-3-1;/h2-9,19H,10-11H2,1H3,(H,20,21);1-5H;/q2*-1;+2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 2.5 mg/mL (5.96 mM; Need ultrasonic). H2O : < 0.1 mg/mL (insoluble).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
The estimate of the apparent terminal half-life of Ferroquine is 15.9 days. However, the equally active principal metabolite Desmethyl ferroquine (DMFQ) has a longer t1/2z, with an overall mean estimate of 31.4 days.
Products are for research use only. Not for human use.
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