Desmethyl ferroquine


Catalog No. Size PriceQuantity
M23522-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Desmethyl ferroquine (SSR97213) is the active and major metabolite of Ferroquine. Ferroquine is an antimalarial. Desmethyl ferroquine shows significant activity against Chloroquine-susceptible and resistant P. falciparum strains.

Product information

CAS Number: 903546-18-9

Molecular Weight: 419.73

Formula: C22H22ClFeN3

Chemical Name: λ²-iron(2+) 1-{[(7-chloroquinolin-4-yl)amino]methyl}-2-[(methylamino)methyl]cyclopenta-2,4-dien-1-ide cyclopenta-2,4-dien-1-ide

Smiles: [Fe+2].CNCC1=CC=C[C-]1CNC1=CC=NC2=CC(Cl)=CC=C21.[CH-]1C=CC=C1

InChiKey: AKDMMOAFGKYNKP-UHFFFAOYSA-N

InChi: InChI=1S/C17H17ClN3.C5H5.Fe/c1-19-10-12-3-2-4-13(12)11-21-16-7-8-20-17-9-14(18)5-6-15(16)17;1-2-4-5-3-1;/h2-9,19H,10-11H2,1H3,(H,20,21);1-5H;/q2*-1;+2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 2.5 mg/mL (5.96 mM; Need ultrasonic). H2O : < 0.1 mg/mL (insoluble).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

The estimate of the apparent terminal half-life of Ferroquine is 15.9 days. However, the equally active principal metabolite Desmethyl ferroquine (DMFQ) has a longer t1/2z, with an overall mean estimate of 31.4 days.

Products are for research use only. Not for human use.

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