Daurinoline

Daurinoline is an alkaloid that can be isolated from the roots of Menispermum dauricum. Daurinoline may be a potential anti-tumor agent or chemosensitizer for chemo-resistant NSCLC research.

Product information

CAS Number: 2831-75-6

Molecular Weight: 610.74

Formula: C37H42N2O6

Chemical Name: (1R)-1-{[4-(5-{[(1R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-2-hydroxyphenoxy)phenyl]methyl}-7-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-6-ol

Smiles: CN1CCC2=CC(OC)=C(C=C2[C@H]1CC1=CC(OC2C=CC(C[C@@H]3C4=CC(OC)=C(O)C=C4CCN3C)=CC=2)=C(O)C=C1)OC

InChiKey: APIHNXDZCYDPTF-FIRIVFDPSA-N

InChi: InChI=1S/C37H42N2O6/c1-38-14-12-25-19-33(41)34(42-3)21-28(25)30(38)16-23-6-9-27(10-7-23)45-35-18-24(8-11-32(35)40)17-31-29-22-37(44-5)36(43-4)20-26(29)13-15-39(31)2/h6-11,18-22,30-31,40-41H,12-17H2,1-5H3/t30-,31-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Daurinoline inhibits the proliferation, migration, invasion and EMT phenotype of chemo-resistant NSCLC cells.

Products are for research use only. Not for human use.