D-Tubocurarine chloride pentahydrate


Catalog No. Size PriceQuantity
M24004-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

D-Tubocurarine chloride pentahydrate is the chloride salt form of Tubocurarine, a nicotinic acetylcholine receptors (AChR) antagonist, and can be used as a skeletal muscle relaxant during surgery or mechanical ventilation. D-Tubocurarine chloride pentahydrate is also a potent neuromuscular blocking agent.

Product information

CAS Number: 6989-98-6

Molecular Weight: 771.72

Formula: C37H52Cl2N2O11

Chemical Name: (1S,16R)-9,21-dihydroxy-10,25-dimethoxy-15,15,30-trimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.2³,⁶.1⁸,¹².1¹⁸,²².0²⁷,³¹.0¹⁶,³⁴]hexatriaconta-3,5,8(34),9,11,18(33),19,21,24(32),25,27(31),35-dodecaen-15-ium pentahydrate hydrochloride chloride

Smiles: O.O.O.O.O.[Cl-].Cl.COC1=CC2CCN(C)[C@H]3CC4C=CC(=CC=4)OC4=C5[C@@H](CC6=CC(OC1=CC=23)=C(O)C=C6)[N+](C)(C)CCC5=CC(OC)=C4O

InChiKey: WMIZITXEJNQAQK-GGDSLZADSA-N

InChi: InChI=1S/C37H40N2O6.2ClH.5H2O/c1-38-14-12-24-19-32(42-4)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-37-35-25(20-34(43-5)36(37)41)13-15-39(2,3)29(35)17-23-8-11-30(40)31(18-23)45-33;;;;;;;/h6-11,18-21,28-29H,12-17H2,1-5H3,(H-,40,41);2*1H;5*1H2/t28-,29+;;;;;;;/m0......./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 10 mg/mL (12.96 mM; ultrasonic and warming and heat to 60°C).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Treatment of Caco-2 cells with the AChR antagonist Tubocurarine (10 µM) induces a disorganization of adherents junctions. Buffalo milk-derived products (MBCP) (18 µM) attenuates Tubocurarine AChR antagonist effects on Caco-2 cells adherens junctions.

Products are for research use only. Not for human use.

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