PF-06795071


Catalog No. Size PriceQuantity
M24040-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

PF-06795071 is a potent and selective covalent MAGL inhibitor with an IC50 of 3 nM.

Product information

CAS Number: 2075629-81-9

Molecular Weight: 399.34

Formula: C18H17F4N3O3

Chemical Name: (2R)-1,1,1-trifluoro-3-hydroxypropan-2-yl (1R,5S)-6-[1-(4-fluorophenyl)-1H-pyrazol-3-yl]-3-azabicyclo[3.1.0]hexane-3-carboxylate

Smiles: OC[C@@H](OC(=O)N1C[C@@H]2C([C@@H]2C1)C1C=CN(N=1)C1=CC=C(F)C=C1)C(F)(F)F

InChiKey: MEDCQBUTCWNKGW-XFDYKOMQSA-N

InChi: InChI=1S/C18H17F4N3O3/c19-10-1-3-11(4-2-10)25-6-5-14(23-25)16-12-7-24(8-13(12)16)17(27)28-15(9-26)18(20,21)22/h1-6,12-13,15-16,26H,7-9H2/t12-,13+,15-,16?/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PF-06795071 shows excellent selectivity against FAAH with an IC50 of 3.1 μM.

Products are for research use only. Not for human use.

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