Description
CHMFL-KIT-033 is a potent and selective inhibitor of c-KIT T670I mutant for gastrointestinal stromal tumors (GISTs), with an IC50 of 0.045 μM.
Product information
CAS Number: 2351801-41-5
Molecular Weight: 415.42
Formula: C23H18FN5O2
Chemical Name: N'-(3-fluorophenyl)-N-{3-[(E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}propanediamide
Smiles: O=C(CC(=O)NC1=CC2NN=C(/C=C/C3=CC=CC=N3)C=2C=C1)NC1=CC(F)=CC=C1
InChiKey: OLZDZYHEIBZXCI-CSKARUKUSA-N
InChi: InChI=1S/C23H18FN5O2/c24-15-4-3-6-17(12-15)26-22(30)14-23(31)27-18-7-9-19-20(28-29-21(19)13-18)10-8-16-5-1-2-11-25-16/h1-13H,14H2,(H,26,30)(H,27,31)(H,28,29)/b10-8+
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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