Sparfosic acid trisodium


Catalog No. Size PriceQuantity
M24209-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Sparfosic acid trisodium, is a potent inhibitor of aspartate transcarbamoyl transferase, with anti-tumor and antimetabolite activity. Aspartate transcarbamoyl transferase catalyzes the second step of de novo pyrimidine biosynthesis.

Product information

CAS Number: 70962-66-2

Molecular Weight: 321.06

Formula: C6H7NNa3O8P

Chemical Name: trisodium (2S)-2-(2-hydrogen phosphonatoacetamido)butanedioate

Smiles: [Na+].[Na+].[Na+].[O-]C(=O)C[C@H](NC(=O)CP([O-])(O)=O)C([O-])=O

InChiKey: LKLUEGVLTGGBIX-LHWPGRLPSA-K

InChi: InChI=1S/C6H10NO8P.3Na/c8-4(2-16(13,14)15)7-3(6(11)12)1-5(9)10;;;/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12)(H2,13,14,15);;;/q;3*+1/p-3/t3-;;;/m0.../s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: H2O : 250 mg/mL (778.67 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Sparfosic acid (PALA) treatment causes apoptosis in the resistant Br1 cells. Sparfosic acid (PALA, 300 µM) shows progressive accumulation of cells in S phase and activation of an apoptotic pathway leading to cell death.

Products are for research use only. Not for human use.

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