2-Phospho-L-ascorbic acid trisodium


Catalog No. Size PriceQuantity
M24218-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

2-Phospho-L-ascorbic acid trisodium acts as an antioxidant and a stimulator of hepatocyte growth factor (HGF) production.

Product information

CAS Number: 66170-10-3

Molecular Weight: 322.05

Formula: C6H6Na3O9P

Chemical Name: trisodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-5-oxo-4-(phosphonatooxy)-2,5-dihydrofuran-3-olate

Smiles: [Na+].[Na+].[Na+].[O-]C1[C@H](OC(=O)C=1OP([O-])([O-])=O)[C@@H](O)CO

InChiKey: YRWWOAFMPXPHEJ-OFBPEYICSA-K

InChi: InChI=1S/C6H9O9P.3Na/c7-1-2(8)4-3(9)5(6(10)14-4)15-16(11,12)13;;;/h2,4,7-9H,1H2,(H2,11,12,13);;;/q;3*+1/p-3/t2-,4+;;;/m0.../s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 6 mg/mL (18.63 mM; Need ultrasonic and warming). H2O : 150 mg/mL (465.77 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

2-Phospho-L-ascorbic acid (Asc 2-P) acts as an antioxidant and a stimulator of hepatocyte growth factor (HGF) production. 2-Phospho-L-ascorbic acid is a stable derivative of L-ascorbic acid (AA) and possesses similar biological properties as AA. AA and Asc-2P regulate a number of biological processes. When 2-Phospho-L-ascorbic acid is added together with DHT, DHT-induced DKK-1 mRNA expression in DPCs is significantly attenuated. It is also found that DKK-1 promoter activity is increased by DHT treatmen. When 2-Phospho-L-ascorbic acid is added together with DHT, DHT-induced activation of luciferase activity is significantly repressed.

Products are for research use only. Not for human use.

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