Description
DSPE-PEG(2000)-Amine is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents.
Product information
CAS Number: 474922-26-4
Molecular Weight: 896.23
Formula: C46H94N3O11P
Chemical Name: [2-({[2-(2-aminoethoxy)ethoxy]carbonyl}amino)ethoxy][2,3-bis(octadecanoyloxy)propoxy]phosphinic acid amine
Smiles: N.CCCCCCCCCCCCCCCCCC(=O)OCC(COP(O)(=O)OCCNC(=O)OCCOCCN)OC(=O)CCCCCCCCCCCCCCCCC
InChiKey: AXHRCGLQEUQOIS-UHFFFAOYSA-N
InChi: InChI=1S/C46H91N2O11P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-44(49)56-41-43(42-58-60(52,53)57-38-36-48-46(51)55-40-39-54-37-35-47)59-45(50)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h43H,3-42,47H2,1-2H3,(H,48,51)(H,52,53);1H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 7.14 mg/mL (ultrasonic and warming and heat to 60°C).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
DSPE-PEG(2000)-Amine is coated on the surface of the fluorescein diacetate (FDA) nanocrystals to provide a interface for the antibody coupling. The FDA[DSPE-PEG(2000)Amine]-modified biolabels have a highly stable colloidal suspension with minimized nonspecific interactions. The adsorbed DSPE-PEG(2000)Amine layer causes the FDA nanocrystals to disperse in water and prevents their aggregation, hence conferring colloidal stability.
Products are for research use only. Not for human use.
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