Description
Benzyl-PEG8-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 1330059-91-0
Molecular Weight: 538.65
Formula: C24H42O11S
Chemical Name: 1-phenyl-2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl methanesulfonate
Smiles: CS(=O)(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCC1C=CC=CC=1
InChiKey: HXGZBARQPKDPSS-UHFFFAOYSA-N
InChi: InChI=1S/C24H42O11S/c1-36(25,26)35-22-21-33-18-17-31-14-13-29-10-9-27-7-8-28-11-12-30-15-16-32-19-20-34-23-24-5-3-2-4-6-24/h2-6H,7-23H2,1H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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