6-Maleimidocaproic acid-PFP ester


Catalog No. Size PriceQuantity
M24743-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

6-Maleimidocaproic acid-PFP ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 692739-25-6

Molecular Weight: 377.26

Formula: C16H12F5NO4

Chemical Name: 2,3,4,5,6-pentafluorophenyl 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate

Smiles: O=C(CCCCCN1C(=O)C=CC1=O)OC1C(F)=C(F)C(F)=C(F)C=1F

InChiKey: CIQYBTAUACRWKP-UHFFFAOYSA-N

InChi: InChI=1S/C16H12F5NO4/c17-11-12(18)14(20)16(15(21)13(11)19)26-10(25)4-2-1-3-7-22-8(23)5-6-9(22)24/h5-6H,1-4,7H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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